ESPN 53rd Annual Meeting

ESPN 2021


 
CLINICAL AND METABOLIC CHARACTERISTICS OF CHILDHOOD RENAL MICROLITHIASIS IN DIFFERENT AGE GROUPS
ONUR ERIŞEN 1 GÖKÇEN ERFIDAN 2 EREN SOYALTIN 2 ÖZGÜR ÖZDEMIR ŞIMŞEK 2 SEÇIL ARSLANSOYU ÇAMLAR 3 DEMET ALAYGUT 2 BELDE KASAP DEMIR 4 FATMA MUTLUBAŞ 3

1- UNIVERSITY OF HEALTH SCIENCES, TEPECIK TRAINING AND RESEARCH HOSPITAL. DEPARTMENT OF PEDIATRICS, İZMIR, TURKEY
2- UNIVERSITY OF HEALTH SCIENCES, TEPECIK TRAINING AND RESEARCH HOSPITAL, DEPARTMENT OF PEDIATRICS, DIVISION OF NEPHROLOGY, IZMIR, TURKEY
3- UNIVERSITY OF HEALTH SCIENCES, IZMIR FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS, DIVISION OF NEPHROLOGY, IZMIR, TURKEY
4- İZMIR KATIP CELEBI UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF PEDIATRICS, DIVISION OF NEPHROLOGY AND RHEUMATOLOGY, IZMIR, TURKEY
 
Introduction:

Renal microlithiasis(RM) is a radiological diagnostic term used to define stones<3 mm in size. It was aimed to compare the etiology, clinical and radiological findings of pediatric patients diagnosed with renal microlithiasis in infancy and later years.

Material and methods:

Children under age of 18 who were followed-up with RM between 2010-2019 were analyzed retrospectively. The patients were grouped according to their age of diagnosis. The patients with 0-24 months were included to Group-1, and >24 months were to Group-2. 

Results:

There were 72 patients in Group-1, 18 patients in Group-2. The frequency of hospitalizations was 50% higher in Group-1(p=0.046). Unilateral one RM was more common in Group-2, unilateral multiple RM was in Group-1(p=0.002). Metabolic disorders were detected in 40.3% of Group-1, and in 33.3% of Group-2(p=0.046). The most common metabolic disorder was hypercalciuria(22%) in Group-1, hyperoxaluria(29%) in Group-2. Hypocitraturia(23.8%) and hyperuricosuria(19%) were found more common in Group-2(p=0.043, p=0.044 respectively). The incidental diagnosis(58.3%) was higher in Group-1(p<0.001). In the first evaluation, the number and diameter of RM increased in 29.2% and 19.4% of patients, respectively. After two years of follow-up, the RM disappeared in 90.3% of Group-1 and 95.2% of Group-2. The frequency of unilateral one RM in Group-2 and unilateral multiple RM in Group-1 were statistically higher(p=0.002). In Group-1, RM was mostly located in the lower pole of the right(47.5%) and left kidneys(60.7%), while in the Group-2, it was located in the middle pole for the right(50%) and left kidneys(53.3%). Upper pole location was the rarest. 

Conclusions:

Renal microlithiasis is a common clinical condition in childhood. Since metabolic disorders mostly play a role in the etiology, metabolic tests should be performed not only in infancy but also in advanced childhood and adolescence.